Cart
sales@molnova.com
Home - Products - Apoptosis - Apoptosis - AP-III-a4 hydrochloride

AP-III-a4 hydrochloride

CAS No. 2070014-95-6

AP-III-a4 hydrochloride ( ENOblock hydrochloride )

Catalog No. M25058 CAS No. 2070014-95-6

AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    AP-III-a4 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic.
  • Description
    AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic.AP-III-a4 (ENOblock) (0-10 μM; 24 h) inhibits HCT116 cell viability in a dose-dependent manner.AP-III-a4 directly binds to enolase and inhibits its activity.AP-III-a4 (0-10 μM; 24 or 48 h) inhibits cancer cell migration and invasion, induces cancer cell apoptosis.AP-III-a4 (10 μM; 24 h) can induce glucose uptake and inhibit phosphoenolpyruvate carboxykinase (PEPCK) expression in hepatocytes and kidney cells.
  • Synonyms
    ENOblock hydrochloride
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    IC50: 0.576 uM (enolase)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2070014-95-6
  • Formula Weight
    631.2
  • Molecular Formula
    C31H44ClFN8O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Da-Woon Jung, et al. A Unique Small Molecule Inhibitor of Enolase Clarifies Its Role in Fundamental Biological Processes.ACS Chem. Biol., 2013, 8 (6), pp 1271–1282 [Content Brief]
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 5-Benzylidene-3-ethy...

    5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.

  • TAS6417

    TAS6417 is an EGFR inhibitor and is an efficacious drug candidate for patients with NSCLC.

  • 3-?O-?Acetyloleanoli...

    3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells. Apoptosis was characterized by detection of cell surface annexin V and sub-G1 apoptotic cell populations.

Sign In Join Free